The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 11, 2014

Filed:

Aug. 31, 2012
Applicants:

David Kirkwood Clarke, Chester, NY (US);

Roger Michael Hendry, Atlanta, GA (US);

Stephen A. Udem, New York, NY (US);

Christopher Lee Parks, Boonton, NJ (US);

Inventors:

David Kirkwood Clarke, Chester, NY (US);

Roger Michael Hendry, Atlanta, GA (US);

Stephen A. Udem, New York, NY (US);

Christopher Lee Parks, Boonton, NJ (US);

Assignee:

Wyeth LLC, Madison, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/205 (2006.01); A61K 39/12 (2006.01); C12N 7/01 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention broadly relates to the synergistic attenuation of vesicular stomatitis virus (VSV), More particularly, the invention relates to the identification of combined mutation classes which synergistically attenuate the pathogenicity of VSV vectors in mammals and immunogenic compositions thereof.


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