The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 11, 2014
Filed:
Jul. 26, 2005
Applicants:
Herman Van Vlijmen, Mechelen, BE;
Alexey Alexandrovic Lugovskoy, Woburn, MA (US);
Karl J. M. Hanf, Billerica, MA (US);
Inventors:
Herman Van Vlijmen, Mechelen, BE;
Alexey Alexandrovic Lugovskoy, Woburn, MA (US);
Karl J. M. Hanf, Billerica, MA (US);
Assignee:
Biogen Idec MA Inc., Cambridge, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides peptides, and fragments thereof, and antibodies, or fragments thereof comprising the same, wherein the peptide comprises at least one amino acid substitution compared to wild type 5c8 antibody. The present invention also provides compositions and methods of treating CD154-related diseases or disorders in a subject.