The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2014
Filed:
Dec. 09, 2009
Kalyanasundaram Subramanian, Bangalore, IN;
Sowmya Raghavan, Bangalore, IN;
Anupama Rajan Bhat, Bhavnagar, IN;
Sonali Das, Murshidabad, IN;
Jyoti Bajpai Dikshit, Bangalore, IN;
Rajeev Kumar, Purnia, IN;
Narasimha Mandyam Krishnakumar, Banglore, IN;
Nalini Rajeshwara, Banglore, IN;
Rajesh Radhakrishnan, Thiruvananthapuram, IN;
Srivatsan Raghunathan, Pollachi, IN;
Kalyanasundaram Subramanian, Bangalore, IN;
Sowmya Raghavan, Bangalore, IN;
Anupama Rajan Bhat, Bhavnagar, IN;
Sonali Das, Murshidabad, IN;
Jyoti Bajpai Dikshit, Bangalore, IN;
Rajeev Kumar, Purnia, IN;
Narasimha Mandyam Krishnakumar, Banglore, IN;
Nalini Rajeshwara, Banglore, IN;
Rajesh Radhakrishnan, Thiruvananthapuram, IN;
Srivatsan Raghunathan, Pollachi, IN;
Abstract
The attached disclosure provides a systems approach based on mathematical modelling of the kinetics of essential biochemical pathways involved in organ homeostasis. When this in silico model is coupled with in-vitro and/or in-vivo measurements to quantify drug-induced perturbations, a powerful platform that allows accurate and mechanistic-level prediction of drug-induced organ injury can be generated. The method described in this disclosure demonstrates that several physiological situations can also be accurately modelled in addition to the effect of perturbations induced by drugs. It can also be used along with high-throughput 'omics' data to generate testable hypotheses leading to informed decision-making in drug development.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile