The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Feb. 04, 2014

Filed:

Dec. 03, 2012
Applicants:

Matthias Grauert, Biberach an der Riss, DE;

Daniel Bischoff, Biberach an der Riss, DE;

Georg Dahmann, Warthausen-Birkenhard, DE;

Raimund Kuelzer, Mittelbiberach, DE;

Klaus Rudolf, Warthausen, DE;

Bernd Wellenzohn, Friedrichshafen, DE;

Inventors:

Matthias Grauert, Biberach an der Riss, DE;

Daniel Bischoff, Biberach an der Riss, DE;

Georg Dahmann, Warthausen-Birkenhard, DE;

Raimund Kuelzer, Mittelbiberach, DE;

Klaus Rudolf, Warthausen, DE;

Bernd Wellenzohn, Friedrichshafen, DE;

Assignee:

Boehringer Ingelheim International GmbH, Ingelheim am Rhein, DE;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 401/00 (2006.01); C07D 211/00 (2006.01); C07D 295/00 (2006.01); C07D 421/00 (2006.01); C07D 405/00 (2006.01); C07D 409/00 (2006.01); C07D 413/00 (2006.01); C07D 213/02 (2006.01); C07D 211/60 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to compounds of formula I their use as positive allosteric modulators of mGlu5 receptor activity, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of neurological and psychiatric disorders associated with glutamate dysfunction such as schizophrenia or cognitive decline such as dementia or cognitive impairment. A, B, X, R, R, Rhave meanings given in the description.


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