The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8642559 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 04, 2014

Filed:

Oct. 12, 2007
Applicants:

Michel Baudry, Irvine, CA (US);

Wei Xu, Los Angeles, CA (US);

Inventors:

Michel Baudry, Irvine, CA (US);

Wei Xu, Los Angeles, CA (US);

Assignee:

University of Southern California, Los Angeles, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 7/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

A composition comprising a peptide or a peptidomimetic thereof that inhibits the C-terminal domain truncation of mGluR1α by calpain, wherein the peptide is 10-30 amino acids in length and contains a sequence that is at least 70% homologous to VIKPLTKSYQGSGK. Also disclosed are methods of detecting the C-terminal domain truncation of mGluR1α by calpain, methods of inhibiting the C-terminal domain truncation of mGluR1α in a neuron, and methods of identifying a compound that inhibits the C-terminal domain truncation of mGluR1α.


Find Patent Forward Citations

Baudry, Michel. (2014). C-terminal domain truncation of mglur1α by calpain and uses thereof (U.S. Patent No. 8642559). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8642559

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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