The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8642291 B1

PDF
Full Text
Expired
Date of Patent:
Feb. 04, 2014

Filed:

May. 14, 2012
Applicants:

Shigeyuki Yokoyama, Kanagawa, JP;

Kensaku Sakamoto, Yokohama, JP;

Fumie Iraha, Yokohama, JP;

Inventors:

Shigeyuki Yokoyama, Kanagawa, JP;

Kensaku Sakamoto, Yokohama, JP;

Fumie Iraha, Yokohama, JP;

Assignee:

RIKEN, Wako-shi, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/00 (2006.01); A61K 45/06 (2006.01); C12P 21/02 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Producing proteins incorporating non-natural amino acids can involve introducing genes into and knocking inherent genes out of eukaryote-type cells. Genes to be introduced include genes encoding eukaryote-type aminoacyl tRNA synthetase mutants having enhanced specificity to non-natural amino acids, compared with specificity to similar natural amino acids, and tRNA genes for non-natural amino acids capable of binding to the non-natural amino acids in the presence of the eukaryote-type aminoacyl tRNA synthetase mutants. Inherent genes to be knocked out include genes encoding aminoacyl tRNA synthetase having specificity to natural amino acids and tRNA genes capable of binding to the natural amino acids in the presence of the inherent aminoacyl tRNA synthetase.


Find Patent Forward Citations

Yokoyama, Shigeyuki. (2014). Method for producing proteins comprising non-natural amino acids incorporated therein (U.S. Patent No. 8642291). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8642291

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