The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2014
Filed:
May. 26, 2006
Applicant:
Robert T. Abraham, San Diego, CA (US);
Inventor:
Robert T. Abraham, San Diego, CA (US);
Assignee:
Sanford-Burnham Medical Research Institute, La Jolla, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/42 (2006.01); C12Q 1/68 (2006.01); G01N 33/573 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides an assay for the identification of agents which can modulate TOR-mediated phosphorylation of substrate proteins. The assays of the invention utilize substrate proteins whose amino acid sequence contains the Ser/Thr motif recognized by TOR. Naturally occurring TOR which may be used in the methods of the invention include TOR isolated from a variety of species, particularly mammalian tissues.