The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2014
Filed:
Sep. 12, 2006
Ogari Pacheco, Itapira, BR;
Osvaldo Augusto Sant'anna, São Paulo, BR;
Lucildes Mercure, São Paulo, BR;
Jivaldo Matos, São Paulo, BR;
Márcia Fantini, São Paulo, BR;
Ogari Pacheco, Itapira, BR;
Osvaldo Augusto Sant'Anna, São Paulo, BR;
Lucildes Mercure, São Paulo, BR;
Jivaldo Matos, São Paulo, BR;
Márcia Fantini, São Paulo, BR;
Cristalia Produtos Quimicos Farmaceuticos Ltda., Itapira, BR;
Fundacao de Amparo a Pesquisa do Estado de Sao Paulo-Fapesp, Sao Paulo, BR;
Abstract
The present invention relates to a product named 'immunogenical complex', which comprises an adjuvant characterized by solid particles of highly ordinated nanostructured mesoporous silica, preferably, SBA-15 Silica, and vaccinal antigens of several natures, encapsulated in the referred to adjuvants. The immunogenical complex of the present invention allows the presentation of the antigens that compose it to lymphocytes, in a safe, gradual and extended way, which leads to a more efficient immunological memory, increases the immunogenicity of the antigen and improves the production of antibodies. This ensures an efficient immunological protection with fewer amounts of antigens and/or less repetitions of vaccinal doses. In addition, the characteristics of the immunogenical complex of the present invention promotes effective immunity induction, homogeneous in 'god and bad respondent' individuals.