The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2014
Filed:
Jun. 08, 2009
Aaron K. Sato, Richmond, CA (US);
Daniel J. Sexton, Melrose, MA (US);
Daniel T. Dransfield, Hanson, MA (US);
Robert C. Ladner, Ijamsville, MD (US);
Christophe Arbogast, Viuz-en-Sallaz, FR;
Philippe Bussat, La Roche-sur-Foron, FR;
Hong Fan, PuDong, CN;
Sudha Khurana, San Jose, CA (US);
Karen E. Linder, Kingston, NJ (US);
Edmund R. Marinelli, Lawrenceville, NJ (US);
Palaniappa Nanjappan, Princeton, NJ (US);
Adrian D. Nunn, Lambertville, NJ (US);
Radhakrishna K. Pillai, Cranbury, NJ (US);
Sibylle Pochon, Troinex, CH;
Feng Yan, Grand-Lancy, CH;
Kondareddiar Ramalingam, Dayton, NJ (US);
Ajay Shrivastava, Princeton, NJ (US);
BO Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Mathew A. Von Wronski, Moorestown, NJ (US);
Aaron K. Sato, Richmond, CA (US);
Daniel J. Sexton, Melrose, MA (US);
Daniel T. Dransfield, Hanson, MA (US);
Robert C. Ladner, Ijamsville, MD (US);
Christophe Arbogast, Viuz-en-Sallaz, FR;
Philippe Bussat, La Roche-sur-Foron, FR;
Hong Fan, PuDong, CN;
Sudha Khurana, San Jose, CA (US);
Karen E. Linder, Kingston, NJ (US);
Edmund R. Marinelli, Lawrenceville, NJ (US);
Palaniappa Nanjappan, Princeton, NJ (US);
Adrian D. Nunn, Lambertville, NJ (US);
Radhakrishna K. Pillai, Cranbury, NJ (US);
Sibylle Pochon, Troinex, CH;
Feng Yan, Grand-Lancy, CH;
Kondareddiar Ramalingam, Dayton, NJ (US);
Ajay Shrivastava, Princeton, NJ (US);
Bo Song, Princeton, NJ (US);
Rolf E. Swenson, Princeton, NJ (US);
Mathew A. Von Wronski, Moorestown, NJ (US);
Dyax Corp., Burlington, MA (US);
Bracco Suisse SA, Manno, CH;
Abstract
The present invention provides polypeptides, peptide dimer, and multimeric complexes comprising at least one binding moiety for KDR or VEGF/KDR complex, which have a variety of uses wherever treating, detecting, isolating or localizing angiogenesis is advantageous. Particularly disclosed are synthetic, isolated polypeptides capable of binding KDR or VEGF/KDR complex with high affinity (e.g., having a K<1 μM), and dimer and multimeric constructs comprising these polypeptides.