The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Feb. 04, 2014
Filed:
Jun. 08, 2012
Ikuo Omura, Okayama, JP;
Zhen Yu Jin, Okayama, JP;
Shuzo Yamashita, Okayama, JP;
Hiroo Iwata, Kyoto, JP;
Akira Mochizuki, Numazu, JP;
Ikuo Omura, Okayama, JP;
Zhen Yu Jin, Okayama, JP;
Shuzo Yamashita, Okayama, JP;
Hiroo Iwata, Kyoto, JP;
Akira Mochizuki, Numazu, JP;
Japan Stent Technology Co., Ltd., Okayama, JP;
Tokai University Educational System, Tokyo, JP;
Toyo Advanced Technologies Co., Ltd., Hiroshima, JP;
Hiroo Iwata Institute for Frontier Medical Sciences, Kyoto University, Kyoto, JP;
Abstract
A stent includes a stent body of a cylindrical configuration having outer and inner surfaces, a first coated layer coating at least the outer surface, and a second coated layer coating substantially completely over the first coated layer. The first coated layer is prepared of a first composition comprising a polymer and a vascular intimal hyperplasia inhibitor (preferably argatroban) of a kind, which does not inhibit proliferation of endothelial cells, the weight compositional ratio of the polymer to the inhibitor being within the range of 8:2 to 3:7. On the other hand, the second coated layer is prepared of a polymer alone or a second composition comprising a polymer and a drug, the weight compositional ratio of the drug to 80% by weight of the polymer being less than 20% by weight.