The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Mar. 31, 2011
Jingyi Wang, Jinan, CN;
Chuanwen Fan, Jinan, CN;
Long Zhang, Jinan, CN;
Boyan Xu, Jinan, CN;
Shousheng Yan, Jinan, CN;
Zongru Guo, Jinan, CN;
Minghui Zhang, Jinan, CN;
Dong Lin, Jinan, CN;
Zhantao Zhang, Jinan, CN;
Haojie Zhou, Jinan, CN;
Jingyi Wang, Jinan, CN;
Chuanwen Fan, Jinan, CN;
Long Zhang, Jinan, CN;
Boyan Xu, Jinan, CN;
Shousheng Yan, Jinan, CN;
Zongru Guo, Jinan, CN;
Minghui Zhang, Jinan, CN;
Dong Lin, Jinan, CN;
Zhantao Zhang, Jinan, CN;
Haojie Zhou, Jinan, CN;
Qilu Pharmaceutical Co., Ltd., Jinan, Shandong, CN;
Abstract
Provided are pyrrolyl substituted dihydroindol-2-one derivatives represented by formula (I), pharmaceutically acceptable salts or solvates of said derivatives, or solvates of said salts, which are effective tyrosine kinase inhibitors. Also provided are the preparation methods of the above compounds, pharmaceutical compositions containing these compounds, and the use of these compounds in manufacturing drugs useful for the treatment or adjunctive treatment of tumors medicated by tyrosine kinases or proliferation or migration of tumor cells driven by tyrosine kinases in mammals (including human).