The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Sep. 17, 2009
Kwang DO Choi, Anyang-si, KR;
Yong Tack Lee, Seoul, KR;
Myeong Sik Yoon, Yongin-si, KR;
Hye Suk Hong, Seongnam-si, KR;
IL Hwan Cho, Seoul, KR;
SI Beum Lee, Yongin-si, KR;
Seong Cheol Bang, Nonsan-si, KR;
Da Won OH, Seoul, KR;
Min Kyoung Lee, Yongin-si, KR;
Kwang Do Choi, Anyang-si, KR;
Yong Tack Lee, Seoul, KR;
Myeong Sik Yoon, Yongin-si, KR;
Hye Suk Hong, Seongnam-si, KR;
Il Hwan Cho, Seoul, KR;
Si Beum Lee, Yongin-si, KR;
Seong Cheol Bang, Nonsan-si, KR;
Da Won Oh, Seoul, KR;
Min Kyoung Lee, Yongin-si, KR;
CJ Cheiljedang Corporation, Seoul, KR;
Abstract
The present invention relates to an improved method of preparing adefovir dipivoxil of Formula 1. The method of the present invention is characterized by using dimethylsulfoxide as a reaction solvent, and comprises a process of preparing adefovir dipivoxil of Formula 1 by allowing adefovir of Formula 2 to react with chloromethylpivalate at a reaction temperature of 30 to 50° C. under the presence of dimethylsulfoxide and triethylamine solvents.