The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2014

Filed:

Sep. 29, 2011
Applicants:

Daulet Satpayev, Santa Monica, CA (US);

Robert Kendall Morrison, Santa Monica, CA (US);

Karen Jane Meyrick Morrison, Santa Monica, CA (US);

Jean Gudas, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Michael Torgov, Santa Monica, CA (US);

Zili an, Santa Monica, CA (US);

Inventors:

Daulet Satpayev, Santa Monica, CA (US);

Robert Kendall Morrison, Santa Monica, CA (US);

Karen Jane Meyrick Morrison, Santa Monica, CA (US);

Jean Gudas, Los Angeles, CA (US);

Aya Jakobovits, Beverly Hills, CA (US);

Michael Torgov, Santa Monica, CA (US);

Zili An, Santa Monica, CA (US);

Assignees:

Seattle Genetics, Inc., Bothell, WA (US);

Agensys, Inc., Santa Monica, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/00 (2006.01); C12P 21/08 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antibody drug conjugates (ADC's) that bind to 191P4D12 protein and variants thereof are described herein. 191P4D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, the ADC's of the invention provide a therapeutic composition for the treatment of cancer.


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