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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8637513 B1

PDFFull Text
Date of Patent:
Jan. 28, 2014

Filed:

Oct. 23, 2008

Heterocycle phenyl amide t-type calcium channel antagonists

Applicants:

James C. Barrow, Harleysville, PA (US);

Paul J. Coleman, Wallingford, PA (US);

Thomas S. Reger, Lansdale, PA (US);

Kelly-ann S. Schlegel, Fleetwood, PA (US);

Youheng Shu, Blue Bell, PA (US);

Zhi-qiang Yang, Schwenksville, PA (US);

Inventors:

James C. Barrow, Harleysville, PA (US);

Paul J. Coleman, Wallingford, PA (US);

Thomas S. Reger, Lansdale, PA (US);

Kelly-Ann S. Schlegel, Fleetwood, PA (US);

Youheng Shu, Blue Bell, PA (US);

Zhi-Qiang Yang, Schwenksville, PA (US);

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:

J. Eric Thies

John C. Todaro

Primary Examiner:

James O Wilson

Assistant Examiner:

Cecilia M Jaisle

Int. Cl.
CPC ...
C07D 401/12 (2006.01); A61K 31/517 (2006.01); A61K 31/497 (2006.01); A61K 31/4439 (2006.01); C07D 487/04 (2006.01); A61K 31/5025 (2006.01); C07D 413/12 (2006.01); A61K 31/443 (2006.01); C07D 417/12 (2006.01); A61K 31/4436 (2006.01); C07D 213/63 (2006.01); C07D 239/74 (2006.01); C07D 241/36 (2006.01); C07D 471/02 (2006.01); A61P 25/08 (2006.01); A61P 29/00 (2006.01); A61P 25/18 (2006.01); A61P 25/16 (2006.01); A61P 25/24 (2006.01); A61P 25/22 (2006.01); A61P 9/08 (2006.01); A61P 9/12 (2006.01); A61P 35/00 (2006.01); A61P 31/10 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to heterocycle phenyl amide compounds which are antagonists of T-type calcium channels, and which are useful in the treatment or prevention of disorders and diseases in which T-type calcium channels are involved. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which T-type calcium channels are involved.

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