The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Aug. 31, 2012
Marc Bellotti, Coto de Caza, CA (US);
H. Bryan Brewer, Jr., Potomac, MD (US);
Hassibullah Akeefe, San Ramon, CA (US);
Adam Paul Conner, Warsaw, IN (US);
Timothy Jon Perlman, Pleasanton, CA (US);
Marc Bellotti, Coto de Caza, CA (US);
H. Bryan Brewer, Jr., Potomac, MD (US);
Hassibullah Akeefe, San Ramon, CA (US);
Adam Paul Conner, Warsaw, IN (US);
Timothy Jon Perlman, Pleasanton, CA (US);
HDL Therapeutics LLC, Short Hills, NJ (US);
Abstract
The present invention is directed to systems, apparatus and methods for creating derivatives of at least one form of HDL without substantially affecting LDL. These derivatives of HDL are particles with reduced lipid content, particularly reduced cholesterol content. These particles have the capacity to bind cholesterol and are administered to a patient to enhance cellular cholesterol efflux and reduce cholesterol levels in cells, tissues, organs, and blood vessels. The present method is useful for treating atherogenic vascular disease and may be combined with other therapies such as statins, inhibitors of cholesterol absorption, niacin, anti-inflammatories, exercise and dietary restriction.