The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 28, 2014

Filed:

Aug. 26, 2010
Applicants:

Zhiguo Jake Song, Edison, NJ (US);

Yaling Wang, Westfield, NJ (US);

David M. Tellers, Lansdale, PA (US);

Laura M. Artino, Oakhurst, NJ (US);

David R. Lieberman, London, GB;

Inventors:

Zhiguo Jake Song, Edison, NJ (US);

Yaling Wang, Westfield, NJ (US);

David M. Tellers, Lansdale, PA (US);

Laura M. Artino, Oakhurst, NJ (US);

David R. Lieberman, London, GB;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to synthetic processes useful in the preparation of macrocyclic compounds of Formula (I) that are useful as inhibitors of the hepatitis C virus NS3 protease and have application in the treatment of conditions caused by the hepatitis C virus. The present invention also encompasses intermediates useful in the disclosed synthetic processes and the methods of their preparation.


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