The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Oct. 12, 2006
Rima F. Kaddurah-daouk, Belmont, MA (US);
K. Ranga Rama Krishnan, Chapel Hill, NC (US);
Joseph P. Mcevoy, Durham, NC (US);
Rebecca Ann Baillie, Woodland, CA (US);
Rima F. Kaddurah-Daouk, Belmont, MA (US);
K. Ranga Rama Krishnan, Chapel Hill, NC (US);
Joseph P. McEvoy, Durham, NC (US);
Rebecca Ann Baillie, Woodland, CA (US);
Duke University, Durham, NC (US);
Lipomics Technologies, Inc., Sacramento, CA (US);
Abstract
The present invention has utilized the power of lipidomics to profile lipid metabolites and to characterize changes in lipid metabolism as they relate to CNS disorders. Lipidomic signatures can guide the development of diagnostic, prognostic and surrogate markers for CNS disorders; identification of new targets for drug design based on highlighted perturbed pathways; stratify patients with CNS disorders as to which pathways are impaired, and facilitate the determination of which patients with CNS disorders are candidates for a particular therapy, i.e. provide the tools for a personalized approach to therapy; identify which patients are responding or are developing side effects to a treatment; design of modified antipsychotics that have less metabolic side effects and enhanced activity; overcome the lag phase in response to some treatments; and find better combination therapies for CNS disorders that target the pathways that are impaired (e.g., impairments in lipid and/or carbohydrate metabolism).