The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Nov. 04, 2011
Applicants:
Junmei Chen, Seattle, WA (US);
Dominic W. Chung, Bellevue, WA (US);
Jose Aron Lopez, Seattle, WA (US);
Inventors:
Junmei Chen, Seattle, WA (US);
Dominic W. Chung, Bellevue, WA (US);
Jose Aron Lopez, Seattle, WA (US);
Assignee:
Puget Sound Blood Center, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/56 (2006.01);
U.S. Cl.
CPC ...
Abstract
Novel methods are described for measuring the rate of ADAMTS13-mediated cleavage of von Willebrand Factor (VWF) multimers. Through the use of the reagent, ristocetin, the method can advantageously be performed in the absence of an applied shear stress or added denaturing agent. Also described are methods for diagnosing ADAMTS13-associated disorders and methods for providing improved treatment of those disorders by evaluating the efficacy of the treatment using the methods as described.