The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Nov. 11, 2011
David Ho, New York, NY (US);
Yaoxing Huang, New York, NY (US);
Craig Pace, New York, NY (US);
Ruijiang Song, New York, NY (US);
Qing Fang, New York, NY (US);
David Ho, New York, NY (US);
Yaoxing Huang, New York, NY (US);
Craig Pace, New York, NY (US);
Ruijiang Song, New York, NY (US);
Qing Fang, New York, NY (US);
The Rockefeller University, New York, NY (US);
Abstract
Disclosed herein are fusion antibodies created to provide both an antigen-binding site that targets the CD4 receptor and an antigen-binding site that targets the HIV envelope. The fusion antibodies disclosed herein provide improved potency and breadth against HIV as compared to monospecific antibodies, and additionally provide high barrier against viral resistance. Also disclosed are pharmaceutical formulations and therapeutic methods utilizing such fusion proteins.