The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 8636979 B1

PDF
Full Text
Expired
Date of Patent:
Jan. 28, 2014

Filed:

Dec. 17, 2010
Applicant:

Karim Asehnoune, Nantes, FR;

Inventor:

Karim Asehnoune, Nantes, FR;

Assignees:

Chu Nantes, Nantes, FR;

Universite de Nantes, Nantes, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A61K 39/02 (2006.01); A61K 45/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns a pharmaceutical composition comprising at least one agonist of at least one Toll Like receptor (TLR) chosen from TLR 4 and 9, for use in the prophylactic treatment of septic complications of post-traumatic systemic immunodepression in a patient who has suffered one or more severe traumatic injuries and is hospitalized in particular in an intensive care unit. Preferably, said TLR 4 agonist is monophosphoryl lipid A (MPLA) or deacylated 3-O-monophosphoryl lipid A (3D-MPLA) and said TLR 9 agonist is a CpG oligodeoxynucleotide (CpG ODN).


Find Patent Forward Citations

Asehnoune, Karim. (2014). Tlr 4 and 9 receptors agonists for preventing septic complications of post-traumatic immunodepression in patients hospitalized for severe traumatic injuries (U.S. Patent No. 8636979). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/8636979

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