The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
May. 20, 2011
Jan Kurt Walter Sandler, Heidelberg, DE;
Ingo Bellin, Mannheim, DE;
Dejan Djuric, Mannheim, DE;
Karl Kolter, Limburgerhof, DE;
Holger Ruckdäschel, St. Martin, DE;
Jan Kurt Walter Sandler, Heidelberg, DE;
Ingo Bellin, Mannheim, DE;
Dejan Djuric, Mannheim, DE;
Karl Kolter, Limburgerhof, DE;
Holger Ruckdäschel, St. Martin, DE;
Basf SE, Ludwigshafen, DE;
Abstract
Process for the production of nanoporous foamed active substance-containing preparations, wherein the active substance is present embedded in a pharmaceutically acceptable polymer, wherein, in stage a) loading of a polymeric molding composition or a polymer melt with a propellant is effected at a pressure and at a temperature at which the propellant is in the supercritical state, in stage b) heating of the laden polymer molding compound or melt is carried out under pressure at a temperature which lies in the range from −40 to +60° C., preferably −20 to +55° C., and especially preferably 0 to +50° C. around the glass transition temperature of the unladen (prior to loading) polymeric molding compound and in stage c) a depressurization of the polymeric molding compound or melt laden in stage a) and heated under pressure in stage b) is effected out with a depressurization rate in the range from 15,000 to 200,000 MPa/sec.