The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 28, 2014
Filed:
Apr. 28, 2011
Sungmin Son, Cambridge, MA (US);
Sangwon Byun, Cambridge, MA (US);
Andrea Kristine Bryan, Allston, MA (US);
Thomas Burg, Goettingen, DE;
Amneet Gulati, Cambridge, MA (US);
Jungchul Lee, Seoul, KR;
Scott Manalis, Cambridge, MA (US);
Yao-chung Weng, Cambridge, MA (US);
Sungmin Son, Cambridge, MA (US);
Sangwon Byun, Cambridge, MA (US);
Andrea Kristine Bryan, Allston, MA (US);
Thomas Burg, Goettingen, DE;
Amneet Gulati, Cambridge, MA (US);
Jungchul Lee, Seoul, KR;
Scott Manalis, Cambridge, MA (US);
Yao-Chung Weng, Cambridge, MA (US);
Massachusetts Institute of Technology, Cambridge, MA (US);
Abstract
Method for determining buoyant mass and deformability of a cell. The method includes introducing the cell into a suspended microchannel resonator that includes a constriction near a distal location in the resonator. A first frequency shift in the resonator is monitored as a cell moves to the distal location in the resonator, the first frequency shift being related to the buoyant mass of the cell. Transit time of the cell through the constriction is measured by monitoring a second frequency shift as a result of a change in cell location as it passes through the constriction, whereby deformability is determined from the measured buoyant mass and transit time.