The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2014
Filed:
Dec. 03, 2009
Sang-hyun Pyo, Daejeon, KR;
Jin-suk Cho, Daejeon, KR;
Moon-suk Kim, Daejeon, KR;
Jai-young Song, Daejeon, KR;
Ho-joon Choi, Daejeon, KR;
Sang-Hyun Pyo, Daejeon, KR;
Jin-Suk Cho, Daejeon, KR;
Moon-Suk Kim, Daejeon, KR;
Jai-Young Song, Daejeon, KR;
Ho-Joon Choi, Daejeon, KR;
Samyang Biopharmaceuticals Corporation, Seoul, KR;
Abstract
Provided is a method for preparing a taxane derivative, comprising: carrying out condensation of a phenylisoserine derivatives having a protective group introduced thereto or a mixture of isomers thereof, as a side chain, with a baccatin III derivative or 10-deacetyl-baccatin III derivative to obtain a mixture of isomers; separating the isomers via chromatography; and carrying out a reversion of the stereochemical structure of a selectively separated isomer, which is suitable for producing a taxane derivative in a large scale with high yield.