The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2014
Filed:
Jun. 19, 2006
Applicants:
Henrik Ostergaard, Lyngby, DK;
Anders Klarskov Petersen, Naerum, DK;
Inventors:
Henrik Ostergaard, Lyngby, DK;
Anders Klarskov Petersen, Naerum, DK;
Assignee:
Novo Nordisk Healthcare AG, Zurich, CH;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 35/14 (2006.01); C07K 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to method for selective reduction and derivatization of recombinantly prepared engineered proteins comprising at least one non-native cysteine, wherein the reduction reaction is conducted in the presence of a redox buffer or in the presence of a triarylphosphine reducing agent.