The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2014

Filed:

Apr. 10, 2009
Applicants:

Youichi Yamaguchi, Tokyo, JP;

Takeshi Yanase, Tokyo, JP;

Susumu Muto, Tokyo, JP;

Akiko Itai, Tokyo, JP;

Inventors:

Youichi Yamaguchi, Tokyo, JP;

Takeshi Yanase, Tokyo, JP;

Susumu Muto, Tokyo, JP;

Akiko Itai, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/19 (2006.01); C07C 51/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The compound represented by the following formula (I) and the like have PAI-1 inhibition activity; wherein: Rrepresents a Caryl group which may be substituted or the like; T represents a single bond or the like; m represents 0 or 1; when m is 0, G represents —N—C(═O)—COH or the like; when m is 1, G represents an oxygen atom or the like; Rrepresents a Caryl group which may be substituted or the like; E represents the following formula (II) wherein one of R, R, Rand Rrepresents the formula R-T-, each of the other three independently represents a hydrogen atom or the like, and Rrepresents the formula —X—Y', a hydrogen atom or the like; X represents —CH— or the like; Y′ represents a carboxy group or the like; M represents a single bond or the like.


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