The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2014
Filed:
Jun. 29, 2012
John Walling, Irving, TX (US);
Stephan D. Parent, W. Lafayette, IN (US);
David T. Jonaitis, Lafayette, IN (US);
Robert M. Kral, Jr., Grapevine, TX (US);
John Walling, Irving, TX (US);
Stephan D. Parent, W. Lafayette, IN (US);
David T. Jonaitis, Lafayette, IN (US);
Robert M. Kral, Jr., Grapevine, TX (US);
Reata Pharmaceuticals, Inc., Irving, TX (US);
Abstract
A triterpenoid compound, methyl 2-cyano-3,12-dioxoleana-1,9(11)-dien-28-oate (CDDO methyl ester), has a non-crystalline, glassy solid form and a non-hydrous crystalline form that can prepared, for example, from a saturated methanol solution. The glassy form displays an enhanced bioavailability over the non-hydrous crystalline form. Each form of CDDO methyl ester is a superior candidate for use, typically in solid dosage form, for treating a variety of disease states, generally associated with inflammation.