The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2014

Filed:

Sep. 19, 2012
Applicants:

Kayvan Niazi, Encino, CA (US);

Shahrooz Rabizadeh, Los Angeles, CA (US);

Anne-laure Le NY, South Pasadena, CA (US);

Oleksandr Buzko, Los Angeles, CA (US);

Justin Golovato, Los Angeles, CA (US);

Patrick Soon-shiong, Los Angeles, CA (US);

Inventors:

Kayvan Niazi, Encino, CA (US);

Shahrooz Rabizadeh, Los Angeles, CA (US);

Anne-Laure Le Ny, South Pasadena, CA (US);

Oleksandr Buzko, Los Angeles, CA (US);

Justin Golovato, Los Angeles, CA (US);

Patrick Soon-Shiong, Los Angeles, CA (US);

Assignee:

Nant Holdings IP, LLC, Culver City, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/90 (2006.01); A61K 31/519 (2006.01); A01N 37/18 (2006.01); A61K 38/00 (2006.01); A61P 31/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Antiviral compositions and methods are contemplated that are especially effective in the treatment and prevention of influenza A viruses. Also presented are cellular assays to identify small molecule compounds having antiviral properties, particularly as it relates to detection of influenza A RNA-dependent RNA polymerase activity in a mammalian cell independent of other influenza A components. Preferred assays allow for identification of viral replication inhibitors that do not disrupt normal cellular activity.


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