The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 21, 2014

Filed:

Mar. 24, 2006
Applicants:

Danilo Perrotti, Dublin, OH (US);

Paolo Neviani, Columbus, OH (US);

Ramasamy Santhanam, Columbus, OH (US);

John C. Byrd, Arlington, OH (US);

Guido Marcucci, Powell, OH (US);

Natarajan Muthusamy, Galloway, OH (US);

Ching-shih Chen, Upper Arlington, OH (US);

Inventors:

Danilo Perrotti, Dublin, OH (US);

Paolo Neviani, Columbus, OH (US);

Ramasamy Santhanam, Columbus, OH (US);

John C. Byrd, Arlington, OH (US);

Guido Marcucci, Powell, OH (US);

Natarajan Muthusamy, Galloway, OH (US);

Ching-Shih Chen, Upper Arlington, OH (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention provides for methods of treating a mammal who has a BCR/ABL-mediated leukemia, including chronic myelogenous leukemia (CML), particularly the blast crisis stage of CML, Philadelphia-positive acute lymphoblastic leukemia (Ph'-ALL), and refractory leukemias. The invention also provides for compounds for the treatment of these leukemias and methods of identifying anti-leukemic agents.


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