The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 21, 2014
Filed:
Sep. 07, 2010
Applicants:
Seung Bum Park, Seoul, KR;
Bong Rae Cho, Seoul, KR;
Hyang Yeon Lee, Seoul, KR;
Jong Min Park, Seoul, KR;
Inventors:
Seung Bum Park, Seoul, KR;
Bong Rae Cho, Seoul, KR;
Hyang Yeon Lee, Seoul, KR;
Jong Min Park, Seoul, KR;
Assignee:
SNU R&DB Foundation, Seoul, KR;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61B 5/00 (2006.01); A61B 8/00 (2006.01); A61B 10/00 (2006.01); A61K 49/00 (2006.01);
U.S. Cl.
CPC ...
A61B 5/00 (2013.01);
Abstract
Disclosed herein are compounds useful as two-photon tracers. Also, methods are provided for visualizing intracellular glucose uptake, screening anticancer agents, and diagnosing cancer using the compounds. They exhibit preferential uptake by cancer cells, penetrability sufficient to allow bright section images, high water solubility, high pH resistance and low toxicity in addition to applicability to living cells in deep tissues over a long period of time.