The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2014

Filed:

Aug. 10, 2006
Applicants:

Weiwen Ying, Ayer, MA (US);

Zhenjian Du, Northborough, MA (US);

Kevin Foley, Waltham, MA (US);

Inventors:

Weiwen Ying, Ayer, MA (US);

Zhenjian Du, Northborough, MA (US);

Kevin Foley, Waltham, MA (US);

Assignee:

Synta Pharmaceuticals Corp., Lexington, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/52 (2006.01); A61K 31/4178 (2006.01); A61K 31/4188 (2006.01); A61K 31/437 (2006.01); C07D 473/00 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 417/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formula (I), pharmaceutical compositions comprising compounds of formula (I) and methods of inhibiting Hsp90 in a cell, treating or preventing a proliferation disorder in a mammal and treating cancer in a mammal comprising administering a compound of formula (I) to a patient or a cell Variable Ris an optionally substituted heteroaryl; an optionally substituted 6 to 14-membered aryl; a bicyclic 9-member heterocycle optionally substituted at any substitutable nitrogen or carbon atoms; or a substituent R, defined herein. Ring A is an aryl or a heteroaryl optionally further substituted with one or more substituents in addition to R. Substituent Ris defined herein.


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