The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2014
Filed:
Mar. 06, 2009
Megan L. Shaw, New York, NY (US);
Hans-heinrich Hoffmann, New York, NY (US);
Adolfo Garcia-sastre, New York, NY (US);
Peter Palese, New York, NY (US);
Megan L. Shaw, New York, NY (US);
Hans-Heinrich Hoffmann, New York, NY (US);
Adolfo Garcia-Sastre, New York, NY (US);
Peter Palese, New York, NY (US);
Icahn School of Medicine at Mount Sinai, New York, NY (US);
Abstract
The present invention relates to compounds that modulate the replication of negative-sense, single-stranded RNA viruses, such as influenza virus, and the use of such compounds. The invention relates to methods for increasing the titer of negative-sense, single-stranded RNA viruses, such as influenza virus, in substrates for virus propagation (e.g., tissue culture). The invention also relates to the use of compounds that decrease virus replication as antiviral agents. The invention further relates to methods for identifying compounds that modulate the replication of negative-sense, single-stranded RNA viruses, in particular, influenza virus.