The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2014
Filed:
Aug. 04, 2011
Jeremy D. Semrau, Ann Arbor, MI (US);
Warren Gallagher, Eau Claire, WI (US);
Sukhwan Yoon, Ann Arbor, MI (US);
Jeongdae Im, Ann Arbor, MI (US);
Alan A. Dispirito, Ames, IA (US);
Sung-woo Lee, Hillsboro, OR (US);
Scott Hartsel, Eau Claire, WI (US);
Marcus T. Mcellistrem, Eau Claire, WI (US);
Jeremy D. Semrau, Ann Arbor, MI (US);
Warren Gallagher, Eau Claire, WI (US);
Sukhwan Yoon, Ann Arbor, MI (US);
Jeongdae Im, Ann Arbor, MI (US);
Alan A. DiSpirito, Ames, IA (US);
Sung-Woo Lee, Hillsboro, OR (US);
Scott Hartsel, Eau Claire, WI (US);
Marcus T. McEllistrem, Eau Claire, WI (US);
Iowa State University Research Foundation, Inc., Ames, IA (US);
The Regents of the University of Michigan, Ann Arbor, MI (US);
WiSys Technology Foundation, Madison, WI (US);
Abstract
The present disclosures provides isolated or purified compounds, each of which bind to a metal atom. Generally, the compounds are small in size (e.g, molecular weight of less than about 1 kDa) and peptidic in nature, inasmuch as the compounds comprise amino acids. In some embodiments, the compound comprises a structure of Formula I:M-P-M-Pwherein each of Pand Pis a peptide comprising at least two amino acids, Mis a first metal binding moiety comprising a substituted imidazolone ring, Mis a second metal binding moiety comprising a substituted oxazolone ring, and wherein Mand Mbind to a single metal atom. Also provided are related complexes, conjugates, cells which synthesize the compounds of the present disclosures, substantially homogenous cultures thereof, kits and compositions, and methods of making or using the materials of the present disclosures.