The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2014

Filed:

Nov. 07, 2011
Applicants:

Arokiasamy Devasagayaraj, Plainsboro, NJ (US);

Haihong Jin, Manalapan, NJ (US);

Qingyun Liu, The Woodlands, TX (US);

Brett Marinelli, Hamilton, NJ (US);

Lakshama Samala, Princeton, NJ (US);

Zhi-cai Shi, Monmouth Junction, NJ (US);

Ashok Tunoori, Princeton, NJ (US);

Ying Wang, Plainsboro, NJ (US);

Wenxue Wu, Princeton Junction, NJ (US);

Chengmin Zhang, Kendall Park, NJ (US);

Haiming Zhang, Lawrenceville, NJ (US);

Inventors:

Arokiasamy Devasagayaraj, Plainsboro, NJ (US);

Haihong Jin, Manalapan, NJ (US);

Qingyun Liu, The Woodlands, TX (US);

Brett Marinelli, Hamilton, NJ (US);

Lakshama Samala, Princeton, NJ (US);

Zhi-Cai Shi, Monmouth Junction, NJ (US);

Ashok Tunoori, Princeton, NJ (US);

Ying Wang, Plainsboro, NJ (US);

Wenxue Wu, Princeton Junction, NJ (US);

Chengmin Zhang, Kendall Park, NJ (US);

Haiming Zhang, Lawrenceville, NJ (US);

Assignee:

Lexicon Pharmaceuticals, Inc., The Woodlands, TX (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/36 (2006.01); C07C 229/42 (2006.01); C07C 229/44 (2006.01); C07C 275/42 (2006.01); C07C 311/29 (2006.01); C07D 213/74 (2006.01); C07D 239/34 (2006.01); C07D 239/42 (2006.01); C07D 239/47 (2006.01); C07D 239/48 (2006.01); C07D 241/20 (2006.01); C07D 241/24 (2006.01); C07D 249/06 (2006.01); C07D 251/16 (2006.01); C07D 251/18 (2006.01); C07D 251/22 (2006.01); C07D 251/52 (2006.01); C07D 401/04 (2006.01); C07D 403/04 (2006.01); C07D 403/12 (2006.01); C07D 409/04 (2006.01); C07D 409/12 (2006.01); C07D 413/12 (2006.01); A61K 31/505 (2006.01); A61P 1/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of formulae I and II are disclosed, as well as compositions comprising them and methods of their use to treat, prevent and manage serotonin-mediated diseases and disorders:


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