The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2014
Filed:
May. 11, 2012
Applicants:
Shaomeng Wang, Saline, MI (US);
Wei Sun, Ann Arbor, MI (US);
Angelo Aguilar, Ann Arbor, MI (US);
Carlos Garcia-echeverria, Paris, FR;
Inventors:
Shaomeng Wang, Saline, MI (US);
Wei Sun, Ann Arbor, MI (US);
Angelo Aguilar, Ann Arbor, MI (US);
Carlos Garcia-Echeverria, Paris, FR;
Assignees:
The Regents of the University of Michigan, Ann Arbor, MI (US);
Sanofi, Paris, FR;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4015 (2006.01); C07D 209/96 (2006.01); C07D 273/04 (2006.01); C07D 401/14 (2006.01);
U.S. Cl.
CPC ...
Abstract
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases.