The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2014

Filed:

Jan. 31, 2008
Applicants:

Juan Jose Almena-perea, Hanau, DE;

Monika Brink, Schwabenheim, DE;

Gerhard Geiβ, Hanau, DE;

Renat Kadyrov, Hanau, DE;

Thorsten Meyer, Schwabenheim, DE;

Inventors:

Juan Jose Almena-Perea, Hanau, DE;

Monika Brink, Schwabenheim, DE;

Gerhard Geiβ, Hanau, DE;

Renat Kadyrov, Hanau, DE;

Thorsten Meyer, Schwabenheim, DE;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 43/00 (2006.01); A61K 31/55 (2006.01); C07D 487/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

This invention relates to a process for the hydrogenation of a ketooxime to selectively form an aminoalcohol stereoisomer, and, in particular, to a process for the hydrogenation of 4,5-dihydro-imidazo[4,5,1-jk][1]benzazepin-2,6,7[1H]-trione-6-oxime or a salt thereof to selectively form a stereoisomer of 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one or a salt thereof. This invention also relates to the use of the 6-amino-7-hydroxy-4,5,6,7-tetrahydro-imidazo[4,5,1-jk][1]-benzazepin-2[1H]-one hydrogenation product or a salt thereof to selectively make a stereoisomer of zilpaterol or a salt thereof, as well as the use of such a zilpaterol stereoisomer or salt in methods of treatment and medicaments for animals.


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