The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2014

Filed:

Feb. 05, 2010
Applicants:

Frank Otto Gombert, Binningen, CH;

Alexander Lederer, Basel, CH;

Daniel Obrecht, Bättwil, CH;

Barbara Romagnoli, Binningen, CH;

Christian Bisang, Basel, CH;

Christian Ludin, Oberwil, CH;

Inventors:

Frank Otto Gombert, Binningen, CH;

Alexander Lederer, Basel, CH;

Daniel Obrecht, Bättwil, CH;

Barbara Romagnoli, Binningen, CH;

Christian Bisang, Basel, CH;

Christian Ludin, Oberwil, CH;

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Specific template-fixed β-hairpin peptidomimetics of the general formula (I) wherein the single elements T or P are α-amino acid residues connected from the carbonyl (C═O) point of attachment to the nitrogen (N) of the next element in clockwise direction and wherein said elements, depending on their positions in the chain, are defined in the description and the claims have the property to act on the receptor CXCR7. Thus, these β-hairpin peptidomimetics can be useful in the treatment or prevention of diseases or conditions in the area of dermatological disorders, metabolic diseases, inflammatory diseases, fibrotic diseases, infectious diseases, neurological diseases, cardiovascular diseases, respiratory diseases, gastro-intestinal tract disorders, urological diseases, ophthalmic diseases, stomatological diseases, haematological diseases and cancer; or the mobilization of stem cells.


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