The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 14, 2014
Filed:
May. 06, 2004
Martin Wald, Hamburg, DE;
Oliver Cromwell, Suesel-Fassendorf, DE;
Andreas Nandy, Hamburg, DE;
Helga Kahlert, Hamburg, DE;
Bernhard Weber, Hamburg, DE;
Helmut Fiebig, Schwarzenbek, DE;
Martin Wald, Hamburg, DE;
Oliver Cromwell, Suesel-Fassendorf, DE;
Andreas Nandy, Hamburg, DE;
Helga Kahlert, Hamburg, DE;
Bernhard Weber, Hamburg, DE;
Helmut Fiebig, Schwarzenbek, DE;
Merck Patent GmbH, Darmstadt, DE;
Abstract
The present invention relates to the preparation and use of variants of the group 5 allergen of the Pooideae which are characterized by reduced IgE reactivity compared with the known wild-type allergens and at the same time by substantially retained reactivity with T lymphocytes. These hypoallergenic allergen variants can be employed for the specific immunotherapy (hyposensitization) of patients having grass pollen allergy or for the preventative immunotherapy of grass pollen allergies.