The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 14, 2014

Filed:

Dec. 22, 2011
Applicants:

David A. Edwards, Cambridge, MA (US);

Richard P. Batycky, Newton, MA (US);

Lloyd Johnston, Newton, MA (US);

Inventors:

David A. Edwards, Cambridge, MA (US);

Richard P. Batycky, Newton, MA (US);

Lloyd Johnston, Newton, MA (US);

Assignee:

Civitas Therapeutics, Inc., Chelsea, MA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/14 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method for delivering an agent to the pulmonary system, in a single, breath-activated step or a single breath, comprises administering from a receptacle enclosing a mass of particles, to a subject's respiratory tract, particles which have a tap density of less than 0.4 g/cmand deliver at least about 50% of the mass of particles. The particles are capable of carrying agents. The agent is (1) part of the spray-drying pre-mixture and thereby incorporated into the particles, (2) added to separately-prepared particles so that the agent is in chemical association with the particles or (3) blended so that the agent is mixed with, and co-delivered with the particles. Respirable compositions comprising carrier particles having a tap density of less than 0.4 g/cmand a composition comprising an agent are also disclosed. Methods of delivering these respirable compositions are also included.


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