The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Nov. 02, 2009
Silvia Ceragioli, Milan, IT;
Giovanni Ciarciello, Cesano Maderno, IT;
Salvatore Incandela, Barasso, IT;
Pietro Minotti, Giussano, IT;
Silvia Ceragioli, Milan, IT;
Giovanni Ciarciello, Cesano Maderno, IT;
Salvatore Incandela, Barasso, IT;
Pietro Minotti, Giussano, IT;
Bracco Imaging S.p.A., Milan, IT;
Abstract
The present invention relies on a process for the preparation of non ionic iodinated contrast agents and, in more details, it relates to a process for the preparation of Iopamidol in high yields and with a high degree of purity. In more details, the invention discloses a process for the preparation of a compound of formula (III) comprising the condensation reaction a compound of formula (II) with 2-amino-1,3-propandiol, being said reaction carried out in an aprotic dipolar solvent and in the presence of an alkaline or alkaline rare earth metal oxide or hydroxide.