The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Mar. 04, 2010
Sang Eun Kim, Seoul, KR;
Byung Chul Lee, Seoul, KR;
Byung Seok Moon, Seoul, KR;
Yu Kyeong Kim, Seoul, KR;
Sang Eun Kim, Seoul, KR;
Byung Chul Lee, Seoul, KR;
Byung Seok Moon, Seoul, KR;
Yu Kyeong Kim, Seoul, KR;
SNU R&DB Foundation, Seoul, KR;
Abstract
A method for preparing [F]fallypride is disclosed, which comprises a first step for trapping a fluorine-18 to a polymer ion exchange cartridge; a second step for extraction of fluorine-18 by inputting low base concentrations: 5.0˜25 μL of 40% TBAHCOor K2.2.2./KCO(5˜25 mg/0.5˜3.0 mg) as a phase-transfer catalyst in a mixture of alcohol/water (1.0/0.2 (v/v)) or alcohol as a solvent into the polymer ion exchange cartridge trapped by the fluorine-18; a third step for preparing a [F]fallypride product by removing the solvent from the trapped fluorine-18, by inputting tosylate precursor in CHCN as a solvent into a reactor and by reacting the same for 5˜35 minutes at 50˜120° C.; and a fourth step for preparing a pure [F]fallypride by purifying the prepared [F]fallypride product.