The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2014

Filed:

Sep. 18, 2009
Applicants:

Marcello Allegretti, L'Aquila, IT;

Andrea Aramini, L'Aquila, IT;

Gianluca Bianchini, L'Aquila, IT;

Maria Candida Cesta, L'Aquila, IT;

Inventors:

Marcello Allegretti, L'Aquila, IT;

Andrea Aramini, L'Aquila, IT;

Gianluca Bianchini, L'Aquila, IT;

Maria Candida Cesta, L'Aquila, IT;

Assignee:

Dompe S.p.A., L'Aquila AQ, IT;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/421 (2006.01); A61K 31/426 (2006.01); C07D 263/48 (2006.01); C07D 277/42 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention relates to (R,S) 2-aryl-propionic acids and derivatives, their single enantiomer (S) and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacerbated recruitment of polymorphonucleated neutrophils (PIvTN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of transient cerebral ischemia, bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and damages caused by ischemia and reperfusion.


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