The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Aug. 03, 2011
Applicants:
Peter X. Wang, Creve Coeur, MO (US);
Tao Jiang, Chesterfield, MO (US);
David W. Berberich, St. Peters, MO (US);
Subo Liao, Ballwin, MO (US);
Inventors:
Peter X. Wang, Creve Coeur, MO (US);
Tao Jiang, Chesterfield, MO (US);
David W. Berberich, St. Peters, MO (US);
Subo Liao, Ballwin, MO (US);
Assignee:
Mallinckrodt LLC, Hazelwood, MO (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 489/02 (2006.01); C07D 489/08 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides processes for the demethylation of an N-methyl morphinan comprising a ketone functional group. In particular, the invention provides methods for the protection of the ketone functional group such that impurities are not generated during the demethylation of the N-methyl morphinan.