The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2014

Filed:

May. 08, 2009
Applicants:

Hajime Nawata, Fukuoka, JP;

Toshihiko Yanase, Fukuoka, JP;

Takayoshi Nakagawa, Kawasaki, JP;

Inventors:

Hajime Nawata, Fukuoka, JP;

Toshihiko Yanase, Fukuoka, JP;

Takayoshi Nakagawa, Kawasaki, JP;

Assignees:

Aska Pharmaceutical Co., Ltd., Tokyo, JP;

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 311/78 (2006.01); A61K 31/35 (2006.01);
U.S. Cl.
CPC ...
Abstract

Disclosed is a method for screening a compound having an activity that selectively modulates an androgen receptor, comprising a step of measuring the mRNA expression level of prostate-specific antigen or the production level of prostate-specific antigen in prostate cancer cells by contacting a test substance with the prostate cancer cells, and a step of measuring the mRNA expression level of uncoupling protein 1 or the production level of uncoupling protein 1 in adipocytes by contacting a test substance with the adipocytes. Additionally disclosed is a selective androgen receptor modulator, comprising as an active ingredient thereof a compound represented by any of structural formulas (I) to (III), and a composition for preventing or treating a lifestyle-related disease, comprising as an active ingredient thereof said selective androgen receptor modulator.


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