The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2014

Filed:

Mar. 19, 2010
Applicants:

Akito Yasuhara, Toshima-ku, JP;

Shuji Yamamoto, Toshima-ku, JP;

Hiroshi Ohta, Toshima-ku, JP;

Yoshihisa Shirasaki, Toshima-ku, JP;

Kazunari Sakagami, Toshima-ku, JP;

Masato Hayashi, Toshima-ku, JP;

Tsuyoshi Shibata, Toshima-ku, JP;

Youichi Shimazaki, Toshima-ku, JP;

Yuko Araki, Toshima-ku, JP;

Kumi Abe, Toshima-ku, JP;

Xiang-min Sun, Toshima-ku, JP;

Inventors:

Akito Yasuhara, Toshima-ku, JP;

Shuji Yamamoto, Toshima-ku, JP;

Hiroshi Ohta, Toshima-ku, JP;

Yoshihisa Shirasaki, Toshima-ku, JP;

Kazunari Sakagami, Toshima-ku, JP;

Masato Hayashi, Toshima-ku, JP;

Tsuyoshi Shibata, Toshima-ku, JP;

Youichi Shimazaki, Toshima-ku, JP;

Yuko Araki, Toshima-ku, JP;

Kumi Abe, Toshima-ku, JP;

Xiang-Min Sun, Toshima-ku, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); C07D 405/12 (2006.01); C07D 409/12 (2006.01); C07D 405/14 (2006.01); A01N 43/64 (2006.01); A01N 43/50 (2006.01); A61K 31/41 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention aims to provide novel compounds of formula [I] or pharmaceutically acceptable salts thereof that are based on a glycine uptake inhibiting action and which are useful in the prevention or treatment of such diseases as schizophrenia, Alzheimer's disease, cognitive dysfunction, dementia, anxiety disorders (generalized anxiety disorder, panic disorder, obsessive-compulsory disorder, social anxiety disorder, posttraumatic stress disorder, specific phobia, acute stress disorder, etc.), depression, drug addiction, spasm, tremor, and sleep disorder:


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