The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 07, 2014

Filed:

Mar. 21, 2012
Applicants:

Xiaoqi Chen, Palo Alto, CA (US);

Kang Dai, Albany, CA (US);

Jason Duquette, South San Francisco, CA (US);

Michael W. Gribble, Jr., San Francisco, CA (US);

Justin N. Huard, Seattle, WA (US);

Kathleen S. Keegan, Bainbridge Island, WA (US);

Zhihong LI, Millbrae, CA (US);

Sarah E. Lively, San Carlos, CA (US);

Lawrence R. Mcgee, Pacifica, CA (US);

Mark L. Ragains, Fort Worth, TX (US);

Xianghong Wang, Dublin, CA (US);

Margaret F. Weidner, Woodinville, WA (US);

Jian Zhang, Foster City, CA (US);

Inventors:

Xiaoqi Chen, Palo Alto, CA (US);

Kang Dai, Albany, CA (US);

Jason Duquette, South San Francisco, CA (US);

Michael W. Gribble, Jr., San Francisco, CA (US);

Justin N. Huard, Seattle, WA (US);

Kathleen S. Keegan, Bainbridge Island, WA (US);

Zhihong Li, Millbrae, CA (US);

Sarah E. Lively, San Carlos, CA (US);

Lawrence R. McGee, Pacifica, CA (US);

Mark L. Ragains, Fort Worth, TX (US);

Xianghong Wang, Dublin, CA (US);

Margaret F. Weidner, Woodinville, WA (US);

Jian Zhang, Foster City, CA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/505 (2006.01); C07D 487/12 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula I are useful inhibitors of CDK 4, CDK6, and FLT3. Such compounds are useful in treating cancer and various other disease conditions. Compounds of Formula I have the following structure: and the definitions of the other variables are provided herein.


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