The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
May. 16, 2011
Amjad Ali, Freehold, NJ (US);
Lin Yan, East Brunswick, NJ (US);
Pei Huo, Millburn, NJ (US);
Ravi Nargund, East Brunswick, NJ (US);
Amjad Ali, Freehold, NJ (US);
Lin Yan, East Brunswick, NJ (US);
Pei Huo, Millburn, NJ (US);
Ravi Nargund, East Brunswick, NJ (US);
Merck Sharp & Dohme Corp., Rahway, NJ (US);
Abstract
A compound having the structure (I) or a pharmaceutically acceptable salt thereof, wherein Ris hydrogen, deuterium, —OH, —OCalkyl, or halogen; Ris hydrogen, deuterium, or Calkyl; Rand Rare independently hydrogen, —Calkyl, —OH, —OCalkyl, or halogen; Rand Rare independently —Calkyl, —(CH)OH, or —OCalkyl, or, together with the nitrogen atom to which they are attached, form a 4- to 7-membered heterocyclic ring containing one nitrogen atom and 0 or 1 oxygen atoms, wherein said ring is unsubstituted or mono-, di- or tri-substituted with halogen or —Calkyl; R15 is —C(O)OH, —C(O)OCHCHNCH)wherein n is 0, 1 or 2, —C(O)NHCH(R)OR, or —C(O)NHCH(R)C(O)NHCH(R)C(O)OR; Ris hydrogen, Calkyl, or (CH)NRRR; R, R, R, R, R, R, R, R, R, R, R, R, and Rare independently hydrogen or —Calkyl; and stereoisomers thereof, and pharmaceutically acceptable salts thereof, and pharmaceutically acceptable salts of stereoisomers thereof.