The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Sep. 12, 2007
Applicants:
Jeffrey Flier, Newton, MA (US);
Maria Koulmanda, Brookline, MA (US);
Terry B. Strom, Brookline, MA (US);
Inventors:
Jeffrey Flier, Newton, MA (US);
Maria Koulmanda, Brookline, MA (US);
Terry B. Strom, Brookline, MA (US);
Assignees:
Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);
The General Hospital Corporation, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/48 (2006.01); A61K 38/55 (2006.01); C07K 14/81 (2006.01); A61K 39/00 (2006.01); A61K 39/395 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
Methods and compositions for treating patients (e.g., patients who are insulin resistant, patients who have diabetes, or are at risk for developing diabetes) are disclosed herein. The methods can include administration of an a1 antitrypsin (AAT) polypeptide or an agent, such as a nucleic acid molecule or organic compound, that promotes the expression or activity of a1-antitrypsin.