The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Feb. 13, 2013
Abbvie Deutschland Gmbh & Co. KG, Wiesbaden, DE;
Robert L. Roden, Foster City, CA (US);
Richard J. Gorczynski, Westminister, CO (US);
Michael J. Gerber, Denver, CO (US);
AbbVie Deutschland GmbH & Co. KG, Wiesbaden, DE;
Abstract
A method for enhancing glycemic control and/or insulin sensitivity in a human subject having diabetic nephropathy and/or metabolic syndrome comprises administering to the subject a selective endothelin A (ET) receptor antagonist in a glycemic control and/or insulin sensitivity enhancing effective amount. A method for treating a complex of comorbidities in an elderly diabetic human subject comprises administering to the subject a selective ETreceptor antagonist in combination or as adjunctive therapy with at least one additional agent that is (i) other than a selective ETreceptor antagonist and (ii) effective in treatment of diabetes and/or at least one of said comorbidities other than hypertension. A therapeutic combination useful in such a method comprises a selective ETreceptor antagonist and at least one antidiabetic, anti-obesity or antidyslipidemic agent other than a selective ETreceptor antagonist.