The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
May. 22, 2007
Applicants:
Cristal I. Gama, Los Angeles, CA (US);
Sarah E. Tully, Olmstead, OH (US);
Linda C. Hsieh-wilson, San Marino, CA (US);
Inventors:
Cristal I. Gama, Los Angeles, CA (US);
Sarah E. Tully, Olmstead, OH (US);
Linda C. Hsieh-Wilson, San Marino, CA (US);
Assignee:
California Institute of Technology, Pasadena, CA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Chondroitin sulfate polysaccharides with defined sulfation patterns can be synthesized. These chondroitin polysaccharides can be used to identify chondroitin sulfate binding proteins. Further, compounds that modulate the activity of chondroitin sulfate binding proteins can be identified. For example, TNF-α was found to bind specifically to CS-E and CS-E can be used to modulate the interaction of TNF-α with the TNF receptor.