The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 07, 2014
Filed:
Apr. 27, 2011
Applicants:
Abedelnasser Abulrob, Orleans, CA;
Mehdi Arbabi-ghahroudi, Ottawa, CA;
Danica Stanimirovic, Greely, CA;
Inventors:
Abedelnasser Abulrob, Orleans, CA;
Mehdi Arbabi-Ghahroudi, Ottawa, CA;
Danica Stanimirovic, Greely, CA;
Assignee:
National Research Council of Canada, Ottawa, Ontario, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); C07K 16/28 (2006.01); G01N 33/53 (2006.01);
U.S. Cl.
CPC ...
Abstract
Anti-ICAM-1 VH single-domain antibodies (sdAbs) are generated by immunizing a llama with recombinant ICAM-1. These antibodies are linked to an imaging moiety for in vivo or ex vivo imaging of ICAM-1-related pathological conditions including atherosclerotic plaques. The antibodies may also be linked to a therapeutic agent to specifically target and treat ICAM-1-related pathological conditions.